Neurotropic alphaviruses can propagate without capsid

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Neurotropic alphaviruses can propagate without capsid

Alphaviruses are a group of enveloped viruses transmitted by mosquitoes. Many alphaviruses are neurotropic, being able to produce encephalitis in humans and animals. Among alphaviruses, both Semliki Forest (SFV) and Sindbis virus (SIN) have been extensively studied as models of viral pathogenicity. In mice, SFV and SIN can infect neurons in the central nervous system and virulent strains induce...

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ژورنال

عنوان ژورنال: Oncotarget

سال: 2016

ISSN: 1949-2553

DOI: 10.18632/oncotarget.13993